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The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial

Abstract:

Epidemiological data suggest low serum 25-hydroxyvitamin D3 (25-OH-D3) levels are associated with radiological progression of knee osteoarthritis (OA). This study aimed to assess whether vitamin D supplementation can slow the rate of progression.A 3 year, double-blind, randomised, placebo-controlled trial of 474 patients aged over 50 with radiographically evident knee OA comparing 800 IU cholecalciferol daily with placebo. Primary outcome was difference in rate of medial joint space narrowing...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.joca.2016.05.020

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
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Publisher:
Elsevier Publisher's website
Journal:
Osteoarthritis and Cartilage Journal website
Volume:
24
Issue:
11
Pages:
1858–1866
Publication date:
2016
DOI:
EISSN:
1522-9653
ISSN:
1063-4584
URN:
uuid:f9d0174c-2263-4909-8e6c-723c16ad56ff
Source identifiers:
628332
Local pid:
pubs:628332

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