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A portable microfluidic fluorescence spectrometer device for gamma-H2AX-based biological dosimetry

Abstract:

Following a radiological incident the rapid identification of those individuals exposed to critically high radiation doses is important for initial triage and medical treatment. It has been previously demonstrated that scoring of radiation-induced foci of the phosphorylated histone γ-H2AX, which form at the sites of DNA double-strand breaks, may be used to determine radiation exposure levels from blood samples. Although faster than the 'gold standard' dicentric assay, foci scoring is still im...

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Publication status:
Published

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Journal:
RADIATION MEASUREMENTS More from this journal
Volume:
46
Issue:
9
Pages:
907-911
Publication date:
2011-09-01
DOI:
ISSN:
1350-4487
Language:
English
Keywords:
Pubs id:
pubs:179975
UUID:
uuid:f9cb680b-ce5b-448b-84a7-eef8ba0d43b2
Local pid:
pubs:179975
Source identifiers:
179975
Deposit date:
2012-12-19

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