- Abstract:
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BACKGROUND: Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after the initial attack. For 50 years, primaquine has been used as a hypnozoitocide to radically cure P. vivax infection, but major concerns remain regarding the side-effects of the drug and adherence to the 14-day regimen. This study examined the effectiveness of using the directly-observed therapy (DOT) method for the radical treatment of P. vivax malaria infection, to prevent r...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 282.3KB)
-
- Publisher copy:
- 10.1186/1475-2875-9-308
-
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- Publisher:
- BioMed Central Ltd. Publisher's website
- Journal:
- Malaria Journal Journal website
- Volume:
- 9
- Issue:
- 1
- Pages:
- Article: 308
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
-
1475-2875
- ISSN:
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1475-2875
- URN:
-
uuid:f9c949c2-593f-4292-8904-64b44a9d515b
- Source identifiers:
-
102692
- Local pid:
- pubs:102692
- Copyright holder:
- Takeuchi et al.
- Copyright date:
- 2010
- Notes:
- © 2010 Takeuchi et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Directly-observed therapy (DOT) for the radical 14-day primaquine treatment of Plasmodium vivax malaria on the Thai-Myanmar border.
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Wellcome Trust
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