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A mathematical model of the use of supplemental oxygen to combat surgical site infection

Abstract:

Infections are a common complication of any surgery, often requiring a recovery period in hospital. Supplemental oxygen therapy administered during and immediately after surgery is thought to enhance the immune response to bacterial contamination. However, aerobic bacteria thrive in oxygen-rich environments, and so it is unclear whether oxygen has a net positive effect on recovery. Here, we develop a mathematical model of post-surgery infection to investigate the efficacy of supplemental oxyg...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jtbi.2019.01.021

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Oxford college:
St John's College
Role:
Author
ORCID:
0000-0002-0146-9164
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Mathematical Institute
Role:
Author
Publisher:
Elsevier
Journal:
Journal of Theoretical Biology More from this journal
Volume:
466
Pages:
11-23
Publication date:
2019-01-16
Acceptance date:
2019-01-11
DOI:
ISSN:
0022-5193
Keywords:
Pubs id:
pubs:959308
UUID:
uuid:f9ab3a2f-498c-4ddc-acb5-4cdf68cee79c
Local pid:
pubs:959308
Source identifiers:
959308
Deposit date:
2019-01-12

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