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On the increase of chromosome mutations under random mating.

Abstract:

After a short introduction on karyotypes and chromosome mutations, we review the ways by which a chromosome mutation can increase in a random mating population, despite the mutation's deleterious effect on the fertility of heterozygotes. Random drift, segregation distortion, viability advantage, and recombination modification are the mechanisms considered. When possible, the models are illustrated with examples of chromosome mutations involving autosomes in mammals, but the arguments apply, o...

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Publication status:
Published

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Journal:
Theoretical population biology
Volume:
9
Issue:
2
Pages:
260-281
Publication date:
1976-04-05
DOI:
EISSN:
1096-0325
ISSN:
0040-5809
URN:
uuid:f9a8e3c2-16b6-478b-b4d3-7a9b38d69238
Source identifiers:
487528
Local pid:
pubs:487528

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