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Assembly of the paraflagellar rod and the flagellum attachment zone complex during the Trypanosoma brucei cell cycle.

Abstract:

Trypanosomes possess a single flagellum that is attached to their cell body via the flagellum attachment zone (FAZ). The FAZ is composed of two structures: a cytoplasmic filament complex and four microtubules situated next to it. There is a complex transmembrane crosslinking of this FAZ to the paraflagellar rod (PFR) and axoneme within the flagellum. We have partially purified the FAZ complex and have produced monoclonal antibodies both against the FAZ and the paraflagellar rod. The two antib...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
The Journal of eukaryotic microbiology
Volume:
46
Issue:
2
Pages:
105-109
Publication date:
1999-01-01
DOI:
EISSN:
1550-7408
ISSN:
1066-5234
URN:
uuid:f98ebc0f-84d0-4ffe-83e7-34a93169bda2
Source identifiers:
26302
Local pid:
pubs:26302

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