Journal article icon

Journal article

Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei.

Abstract:

BACKGROUND: Protozoan parasites of the genus Trypanosoma cause disease in a wide range of mammalian hosts. Trypanosoma brucei brucei, transmitted by tsetse fly to cattle, causes a disease (Nagana) of great economic importance in parts of Africa. T. b. brucei also serves as a model for related Trypanosoma species, which cause human sleeping sickness. MATERIALS AND METHODS: Chalcone and acyl hydrazide derivatives are known to retard the growth of Plasmodium falciparum in vitro and inhibit the m...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Molecular medicine (Cambridge, Mass.) More from this journal
Volume:
6
Issue:
8
Pages:
660-669
Publication date:
2000-08-01
EISSN:
1528-3658
ISSN:
1076-1551
Language:
English
Keywords:
Pubs id:
pubs:226501
UUID:
uuid:f9830dee-770c-474e-a272-d1931fb35103
Local pid:
pubs:226501
Source identifiers:
226501
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP