- Abstract:
-
The thermodynamic stability and solution conformational properties of three intramolecular triple helices based on the sequence AGAAGA-x-TCTTCT-x- TCTTCT (x is a non-nucleotide linker) comprising a DNA duplex and DNA, RNA, or 2'-OMeDNA third strands have been compared. The most stable triple helix contains the 2'-OMe third strand, followed by the triplex containing RNA in the third strand. Comparison of the NMR spectroscopic data for the RNA hybrid triplex with those of the all-DNA triplex sh...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1021/ja991949s
-
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- Journal:
- JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Volume:
- 121
- Issue:
- 48
- Pages:
- 11063-11070
- Publication date:
- 1999-12-08
- DOI:
- EISSN:
-
1520-5126
- ISSN:
-
0002-7863
- URN:
-
uuid:f9736d26-ac19-4d90-b5e0-4b867f24521a
- Source identifiers:
-
400251
- Local pid:
- pubs:400251
- Language:
- English
- Copyright date:
- 1999
Journal article
Conformational and thermodynamic properties of parallel intramolecular triple helices containing a DNA, RNA, or 2 '-OMeDNA third strand
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