- Abstract:
-
NKT cells with an invariant Ag receptor (iNKT cells) represent a highly conserved and unique subset of T lymphocytes having properties of innate and adaptive immune cells. They have been reported to regulate a variety of immune responses, including the response to cancers and the development of autoimmunity. The development and activation of iNKT cells is dependent on self-Ags presented by the CD1d Ag-presenting molecule. It is widely believed that these self-Ags are glycosphingolipids (GSLs)...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.4049/jimmunol.1001008
-
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- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 186
- Issue:
- 3
- Pages:
- 1348-1360
- Publication date:
- 2011-02-05
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:f971e9f3-8b53-479f-acc5-fc26a8d50551
- Source identifiers:
-
118141
- Local pid:
- pubs:118141
- Copyright date:
- 2011
Journal article
Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids.
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