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Structural and functional phenotyping in the cone-specific photoreceptor function loss 1 (cpfl1) mouse mutant - a model of cone dystrophies.

Abstract:

PURPOSE: We performed a comprehensive in vivo assessment of retinal morphology and function in cpfl1 (cone photoreceptor function loss 1) mice to better define the disease process in this model of cone dystrophies. METHODS: Mice were examined using electroretinography (ERG), confocal scanning laser ophthalmoscopy (cSLO), and spectral domain optical coherence tomography (SD-OCT). Cross-breeding cpfl1 mutants with mice expressing green fluorescent protein (GFP) under control of red-green cone ...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Advances in experimental medicine and biology More from this journal
Volume:
664
Pages:
593-599
Publication date:
2010-01-01
DOI:
ISSN:
0065-2598
Language:
English
Keywords:
Pubs id:
pubs:372100
UUID:
uuid:f9659b85-13ad-4fc9-8357-574ab9cef3bf
Local pid:
pubs:372100
Source identifiers:
372100
Deposit date:
2013-11-16

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