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Journal article

Patched 1 expression correlates with biochemical relapse in high-risk prostate cancer patients

Abstract:

There is an unmet clinical need for adequate biomarkers to aid risk stratification and management of prostate cancer (PCa) patients. Even within the high-risk PCa category not all patients will invariably have a poor prognosis, and improved stratification of this heterogeneous group is needed. In this context, components of the hedgehog (Hh) pathway may have promise as biomarkers, as the available evidence suggests increased Hh pathway activity may confer a poorer outcome in advanced and cast...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ajpath.2017.11.019

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
More from this funder
Name:
National Cancer Plan Action 29 Belgium
Grant:
KPC_29_023
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Name:
National Institute for Health Research
Grant:
CL-2008-13-005
More from this funder
Name:
Academy of Medical Sciences
Publisher:
Elsevier
Journal:
American Journal of Pathology More from this journal
Volume:
188
Issue:
3
Pages:
795-804
Publication date:
2018-01-12
Acceptance date:
2017-11-20
DOI:
EISSN:
1525-2191
ISSN:
0002-9440
Pmid:
29339090
Language:
English
Pubs id:
pubs:821428
UUID:
uuid:f95d8484-acc5-453d-9a38-6bbb3851fd62
Local pid:
pubs:821428
Source identifiers:
821428
Deposit date:
2018-02-01

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