- Abstract:
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With the functional demonstration of a role in erythrocyte invasion by Plasmodium falciparum parasites, implications in the aetiology of common conditions that prevail in individuals of African origin, and a wealth of pharmacological knowledge, the stimulatory G protein (Gs) signal transduction pathway presents an exciting target for anti-malarial drug intervention. Having previously demonstrated a role for the G-alpha-s gene, GNAS, in severe malaria disease, we sought to identify other impor...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 129.6KB)
-
- Publisher copy:
- 10.1371/journal.pone.0010017
-
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- Journal:
- PLoS One Journal website
- Volume:
- 5
- Issue:
- 4
- Pages:
- e10017-e10017
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- URN:
-
uuid:f941bbf6-44d3-4749-9863-3c3f8102c337
- Source identifiers:
-
53295
- Local pid:
- pubs:53295
- Language:
- English
- Keywords:
- Copyright date:
- 2010
- Notes:
-
file: :C$$:/Users/dominic/Dropbox/Refs/2010/Auburn et al._2010_Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis.pdf:pdf
keywords: dkcv
mendeley-tags: dkcv
This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose
Journal article
Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis
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Medical Research Council
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