Journal article
Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis
- Abstract:
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With the functional demonstration of a role in erythrocyte invasion by Plasmodium falciparum parasites, implications in the aetiology of common conditions that prevail in individuals of African origin, and a wealth of pharmacological knowledge, the stimulatory G protein (Gs) signal transduction pathway presents an exciting target for anti-malarial drug intervention. Having previously demonstrated a role for the G-alpha-s gene, GNAS, in severe malaria disease, we sought to identify other impor...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 129.6KB)
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- Publisher copy:
- 10.1371/journal.pone.0010017
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Authors
Funding
Medical Research Council
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS One Journal website
- Volume:
- 5
- Issue:
- 4
- Article number:
- e10017
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Source identifiers:
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53295
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:53295
- UUID:
-
uuid:f941bbf6-44d3-4749-9863-3c3f8102c337
- Local pid:
- pubs:53295
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
- Notes:
-
file: :C$$:/Users/dominic/Dropbox/Refs/2010/Auburn et al._2010_Further evidence supporting a role for gs signal transduction in severe malaria pathogenesis.pdf:pdf
keywords: dkcv
mendeley-tags: dkcv This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose
- Licence:
- CC Attribution (CC BY)
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