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Journal article

Neurotropic viruses and Alzheimer's disease: a search for varicella zoster virus DNA by the polymerase chain reaction.

Abstract:

BACKGROUND: In studies on the possible role of viruses in the aetiopathogenesis of Alzheimer's disease, herpes simplex virus type 1 (HSV1) DNA was detected by the polymerase chain reaction (PCR) in a high proportion of normal elderly people and of patients with Alzheimer's disease. The combination of HSV1 and a host factor, the type 4 allele of the gene for apolipoprotein E, is a strong risk factor for the disease. METHODS: Brain specimens were examined for another herpes virus, varicella zos...

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Publication status:
Published

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Publisher copy:
10.1136/jnnp.62.6.586

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of neurology, neurosurgery, and psychiatry More from this journal
Volume:
62
Issue:
6
Pages:
586-589
Publication date:
1997-06-01
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
Language:
English
Keywords:
Pubs id:
pubs:36066
UUID:
uuid:f93f8fd3-576f-47c8-9135-096b6b7aedc9
Local pid:
pubs:36066
Source identifiers:
36066
Deposit date:
2012-12-19

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