Journal article icon

Journal article

Enhanced K(+)-channel-mediated endothelium-dependent local and conducted dilation of small mesenteric arteries from ApoE(-/-) mice.

Abstract:

Agonists that evoke smooth muscle cell hyperpolarization have the potential to stimulate both local and conducted dilation. We investigated whether the endothelium-dependent vasodilators acetylcholine (ACh) and SLIGRL stimulated conducted dilation and whether this was altered by deficiency in apolipoprotein E (ApoE(-/-)).Isolated mesenteric arteries were cannulated, pressurized, and precontracted with phenylephrine. Agonists were either added to the bath to study local dilation or were restri...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/cvr/cvr181

Authors


Expand authors...
Journal:
Cardiovascular research
Volume:
92
Issue:
2
Pages:
199-208
Publication date:
2011-11-05
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
URN:
uuid:f93be2e4-4ae7-4f6d-bb9a-7d714c2e48a9
Source identifiers:
155019
Local pid:
pubs:155019

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP