- Abstract:
-
Agonists that evoke smooth muscle cell hyperpolarization have the potential to stimulate both local and conducted dilation. We investigated whether the endothelium-dependent vasodilators acetylcholine (ACh) and SLIGRL stimulated conducted dilation and whether this was altered by deficiency in apolipoprotein E (ApoE(-/-)).Isolated mesenteric arteries were cannulated, pressurized, and precontracted with phenylephrine. Agonists were either added to the bath to study local dilation or were restri...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/cvr/cvr181
-
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- Journal:
- Cardiovascular research
- Volume:
- 92
- Issue:
- 2
- Pages:
- 199-208
- Publication date:
- 2011-11-05
- DOI:
- EISSN:
-
1755-3245
- ISSN:
-
0008-6363
- URN:
-
uuid:f93be2e4-4ae7-4f6d-bb9a-7d714c2e48a9
- Source identifiers:
-
155019
- Local pid:
- pubs:155019
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Enhanced K(+)-channel-mediated endothelium-dependent local and conducted dilation of small mesenteric arteries from ApoE(-/-) mice.
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