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Journal article

Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes.

Abstract:

The T-box transcription factor Eomes is expressed in cytotoxic immune cells and plays an important role in development, maintenance, and function of these cell types. Identification and separation of cells with differential Eomes expression would allow for better understanding of the transcriptional program governing these cytotoxic lymphocytes. Here, we report the use of an Eomes(gfp)-targeted mouse allele that displays robust fidelity to Eomes protein expression in NK and T cells. Use of th...

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Publication status:
Published

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Publisher copy:
10.1189/jlb.0812400

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of leukocyte biology More from this journal
Volume:
93
Issue:
2
Pages:
307-315
Publication date:
2013-02-01
DOI:
EISSN:
1938-3673
ISSN:
0741-5400
Language:
English
Keywords:
Pubs id:
pubs:365450
UUID:
uuid:f9364bef-785f-4be3-a0ea-95748ce1864f
Local pid:
pubs:365450
Source identifiers:
365450
Deposit date:
2013-11-17

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