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Chapter 22 - Investigating cell-type specific functions of tenascin-C

Abstract:

The extracellular matrix molecule tenascin-C (TNC) has received a lot of attention since its discovery 30 years ago because of its multiple roles in tissue repair, and in pathologies such as chronic inflammation, fibrosis, and cancer. Mouse models with high or no TNC expression have enabled the validation of key roles for TNC in immunity and angiogenesis. In parallel, many approaches including primary cell or organ cultures have shed light on the cellular and molecular mechanisms by which TNC...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/bs.mcb.2017.08.023

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Institution:
University of Oxford
Department:
NDORMS; KIR
Role:
Author
Publisher:
Elsevier
Journal:
Methods in Cell Biology More from this journal
Publication date:
2017-12-01
DOI:
ISSN:
0091-679X
Language:
English
Keywords:
Pubs id:
pubs:811399
UUID:
uuid:f8ed330d-3f4c-44ef-adfc-a1e28af452df
Local pid:
pubs:811399
Source identifiers:
811399
Deposit date:
2018-01-15

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