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Journal article

Bioorthogonal organic chemistry in living cells: novel strategies for labeling biomolecules.

Abstract:

The chemical labeling of biomolecules continues to be an important tool for the study of their function and cellular fate. Attention is increasingly focused on labeling of biomolecules in living cells, since cell lysis introduces many artefacts. In addition, with the advances in biocompatible synthetic organic chemistry, a whole new field of opportunity has opened up, affording high diversity in the nature of the label as well as a choice of ligation reactions. In recent years, several differ...

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Publication status:
Published

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Publisher copy:
10.1039/b412558d

Authors


van Swieten, PF More by this author
Leeuwenburgh, MA More by this author
Kessler, BM More by this author
Overkleeft, HS More by this author
Journal:
Organic and biomolecular chemistry
Volume:
3
Issue:
1
Pages:
20-27
Publication date:
2005-01-05
DOI:
EISSN:
1477-0539
ISSN:
1477-0520
URN:
uuid:f8b003fc-2dcb-4f2d-a507-9db440e6f2e5
Source identifiers:
781
Local pid:
pubs:781

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