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Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non-coding genes.

Abstract:

MOTIVATION: Comparing transcriptomic data with proteomic data to identify protein-coding sequences is a long-standing challenge in molecular biology, one that is exacerbated by the increasing size of high-throughput datasets. To address this challenge, and thereby to improve the quality of genome annotation and understanding of genome biology, we have developed an integrated suite of programs, called Pinstripe. We demonstrate its application, utility and discovery power using transcriptomic a...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Bioinformatics (Oxford, England) More from this journal
Volume:
28
Issue:
23
Pages:
3042-3050
Publication date:
2012-12-01
DOI:
EISSN:
1367-4811
ISSN:
1367-4803
Language:
English
Keywords:
Pubs id:
pubs:482395
UUID:
uuid:f89fb7fe-53dc-407f-8f0a-dfa38bd70ffe
Local pid:
pubs:482395
Source identifiers:
482395
Deposit date:
2014-09-09

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