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Predictive and prognostic markers in a series of patients with head and neck squamous cell invasive carcinoma treated with concurrent chemoradiation therapy.

Abstract:

It has been proposed that diverse anticancer drugs and radiation therapy may induce a mode of cell death with the characteristics of apoptosis. Since apoptosis is under the control of several oncogenes, we analyzed the expression of the protein encoded by the proto-oncogenes bcl-2 and p53. Furthermore, we studied cell proliferation [using PC-10 mAb to proliferating cell nuclear antigen (PCNA)] and vascularization [using the CD-31 mAb and by counting intratumoral microvessel density (IMD)] usi...

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Gasparini, G More by this author
Bevilacqua, P More by this author
Bonoldi, E More by this author
Testolin, A More by this author
Galassi, A More by this author
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Journal:
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume:
1
Issue:
11
Pages:
1375-1383
Publication date:
1995-11-05
ISSN:
1078-0432
URN:
uuid:f89ced4e-8a76-4d60-932a-aa6d566ab7e0
Source identifiers:
486725
Local pid:
pubs:486725

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