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Photoswitchable spiropyran dyads for biological imaging.

Abstract:

The synthesis of a small-molecule dyad consisting of a far-red-emitting silicon rhodamine dye that is covalently linked to a photochromic spironaphthothiopyran unit, which serves as a photoswitchable quencher, is reported. This system can be switched reversibly between the fluorescent and nonfluorescent states using visible light at wavelengths of 405 and 630 nm, respectively, and it works effectively in aqueous solution. Live-cell imaging demonstrates that this dyad has several desirable fea...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1021/acs.orglett.6b01717

Authors


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Department:
Oxford, MPLS, Chemistry
Rivera-Fuentes, P More by this author
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Department:
Oxford, MSD, RDM, RDM Investigative Medicine Division
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Department:
Oxford, MPLS, Chemistry, Organic Chemistry
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Department:
Oxford, MSD, RDM, RDM Investigative Medicine Division
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Funding agency for:
Xiong, Y
Wolfson Foundation More from this funder
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Publisher:
American Chemical Society Publisher's website
Journal:
Organic Letters Journal website
Volume:
18
Issue:
15
Pages:
3666-3669
Publication date:
2016-07-05
Acceptance date:
2016-07-20
DOI:
ISSN:
1523-7052 and 1523-7060
Pubs id:
pubs:636360
URN:
uri:f80e0efb-e867-4d07-80e2-918a41559661
UUID:
uuid:f80e0efb-e867-4d07-80e2-918a41559661
Local pid:
pubs:636360
Language:
English
Keywords:

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