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Goblet cell differentiation in colorectal cancer

Abstract:

Colorectal stem cells give rise to three cell types in the colorectal crypt: enterocytes, enteroendocrince cells and goblet cells. In colorectal cancer this stem cell differentiation is dysregulated and absence of differentiation usually confers a worse prognosis for the patient. In order to understand goblet cell differentiation in colorectal cancer we first investigated novel goblet cell markers. REG4 was found as a marker through examination of our microarray data on 96 colorectal ce...

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Division:
MSD
Department:
Oncology
Role:
Author

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Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:f7cfe096-4a3a-4b87-bd58-499ebfcaa871
Deposit date:
2016-12-21

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