Conference item icon

Conference item

DarTG is a novel toxin-antitoxin system that catalyses the reversible ADP-ribosylation of DNA

Abstract:

The discovery and study of toxin-antitoxin (TA) systems helps us advance our understanding of the strategies prokaryotes employ to regulate cellular processes related to the general stress response, such as defense against phages, growth control, biofilm formation, persistence and programmed cell death. Here we identify and characterise a TA system found in various bacteria, including the global pathogen Mycobacterium tuberculosis and the thermophilic Thermus aquaticus (Taq). The toxin of the...

Expand abstract
Publication status:
Published
Peer review status:
Reviewed (other)

Actions


Access Document


Files:
Publisher copy:
10.6084/m9.figshare.4801957.v1

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Publisher:
Microbiology Society Publisher's website
Host title:
Microbiology Society Annual Conference 2017, 03-09 April 2017, Edinburgh, UK
Publication date:
2017-04-04
DOI:
Keywords:
Pubs id:
pubs:687601
UUID:
uuid:f77527c4-e126-4c7e-b5c5-dff7f4d1bc5c
Local pid:
pubs:687601
Deposit date:
2017-03-30

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP