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Time-series hyperpolarized xenon-129 MRI of lobar lung ventilation of COPD in comparison to V/Q-SPECT/CT and CT

Abstract:
Purpose To derive lobar ventilation in patients with chronic obstructive pulmonary disease (COPD) using a rapid time-series hyperpolarized xenon-129 (HPX) magnetic resonance imaging (MRI) technique and compare this to ventilation/perfusion single-photon emission computed tomography (V/Q-SPECT), correlating the results with high-resolution computed tomography (CT) and pulmonary function tests (PFTs). Materials and methods Twelve COPD subjects (GOLD stages I–I... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1007/s00330-018-5888-y

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Role:
Author
ORCID:
0000-0002-5945-2090
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering
Role:
Author
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Grant:
Biomedical Research Centre, Oxford
Publisher:
Springer Verlag Publisher's website
Journal:
European Radiology Journal website
Volume:
29
Issue:
8
Pages:
4058–4067
Publication date:
2018-12-14
Acceptance date:
2018-11-13
DOI:
EISSN:
1432-1084
ISSN:
0938-7994
Pubs id:
pubs:953008
URN:
uri:f7270bd4-cb29-47ac-a4de-552b86cd8117
UUID:
uuid:f7270bd4-cb29-47ac-a4de-552b86cd8117
Local pid:
pubs:953008

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