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Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials

Abstract:

To improve strategies for the treatment of BRAF-mutant advanced colorectal cancer (aCRC) patients, we examined individual data from patients treated with chemotherapy alone in three randomised trials to identify points on the treatment pathway where outcomes differ from BRAF wild-types.2530 aCRC patients were assessed from three randomised trials. End-points were progression-free survival, response rate, disease control rate, post-progression survival (P-PS) a...

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Publication status:
Published
Peer review status:
Peer Reviewed

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Publisher copy:
10.1093/annonc/mdw645

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Publisher:
Oxford University Press Publisher's website
Journal:
Annals of Oncology Journal website
Volume:
28
Issue:
3
Pages:
562-568
Publication date:
2016-12-19
DOI:
EISSN:
1569-8041
ISSN:
0923-7534
Pubs id:
pubs:667845
URN:
uri:f6f74d8c-ef6e-45aa-adcd-3a1aadd34e98
UUID:
uuid:f6f74d8c-ef6e-45aa-adcd-3a1aadd34e98
Local pid:
pubs:667845
Language:
English
Keywords:

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