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Elevated blood pressure and risk of aortic valve disease: a cohort analysis of 5.4 million UK adults

Abstract:
Aims To test two related hypotheses that elevated blood pressure (BP) is a risk factor for aortic valve stenosis (AS) or regurgitation (AR). Methods and results In this cohort study of 5.4 million UK patients with no known cardiovascular disease or aortic valve disease at baseline, we investigated the relationship between BP and risk of incident AS and AR using multivariable-adjusted Cox regression models. Over a median follow-up of 9.2 years, 20 680 patient... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/eurheartj/ehy486

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Institution:
University of Oxford
Department:
George Institute for Global Health
Role:
Author
More by this author
Institution:
University of Oxford
Department:
George Institute for Global Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
George Institute for Global Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
George Institute for Global Health
Role:
Author
More from this funder
Name:
Australian Health and Medical Research Council
Funding agency for:
Woodward, M
Grant:
Principal Research Fellowship
More from this funder
Name:
Oxford Martin School
Grant:
Deep Medicine programme
More from this funder
Name:
Clarendon Fund
Funding agency for:
Tran, J
More from this funder
Name:
Rhodes Trust
Funding agency for:
Tran, J
More from this funder
Name:
NIHR Oxford Biomedical Research Centre
Funding agency for:
Rahimi, K
Mohseni, H
Rahimian, F
Publisher:
Oxford University Press
Journal:
European Heart Journal More from this journal
Volume:
39
Issue:
39
Pages:
3596–3603
Publication date:
2018-09-12
Acceptance date:
2018-08-07
DOI:
EISSN:
1522-9645
ISSN:
0195-668X
Keywords:
Pubs id:
pubs:891230
UUID:
uuid:f6e5ff51-f860-480b-ab10-a148ca650692
Local pid:
pubs:891230
Source identifiers:
891230
Deposit date:
2018-07-26

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