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Elevated blood pressure and risk of aortic valve disease: a cohort analysis of 5.4 million UK adults

Abstract:
Aims To test two related hypotheses that elevated blood pressure (BP) is a risk factor for aortic valve stenosis (AS) or regurgitation (AR). Methods and results In this cohort study of 5.4 million UK patients with no known cardiovascular disease or aortic valve disease at baseline, we investigated the relationship between BP and risk of incident AS and AR using multivariable-adjusted Cox regression models. Over a median follow-up of 9.2 years, 20 680 patient... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/eurheartj/ehy486

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM Cardiovascular Medicine
More by this author
Institution:
University of Oxford
Department:
George Institute for Global Health
More by this author
Institution:
University of Oxford
Department:
George Institute for Global Health
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
George Institute for Global Health
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
George Institute for Global Health
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Funding agency for:
Tran, J
More from this funder
Funding agency for:
Tran, J
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Publisher:
Oxford University Press Publisher's website
Journal:
European Heart Journal Journal website
Volume:
39
Issue:
39
Pages:
3596–3603
Publication date:
2018-09-12
Acceptance date:
2018-08-07
DOI:
EISSN:
1522-9645
ISSN:
0195-668X
Pubs id:
pubs:891230
URN:
uri:f6e5ff51-f860-480b-ab10-a148ca650692
UUID:
uuid:f6e5ff51-f860-480b-ab10-a148ca650692
Local pid:
pubs:891230

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