Journal article
Inflammatory gene expression associates with hepatitis B virus cccDNA- but not integrant-derived transcripts in HBeAg negative disease
- Abstract:
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Chronic hepatitis B virus (HBV) infection is a global health problem that presents as a spectrum of liver disease, reflecting an interplay between the virus and the host immune system. HBV genomes exist as episomal covalently closed circular DNA (cccDNA) or chromosomal integrants. The relative contribution of these genomes to the viral transcriptome in chronic hepatitis B (CHB) is not well-understood. We developed a qPCR method to estimate the abundance of HBV cccDNA- and integrant-derived vi...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 4.2MB, Terms of use)
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- Publisher copy:
- 10.3390/v14051070
Authors
Funding
Bibliographic Details
- Publisher:
- MDPI
- Journal:
- Viruses More from this journal
- Volume:
- 14
- Issue:
- 5
- Article number:
- 1070
- Place of publication:
- Switzerland
- Publication date:
- 2022-05-17
- Acceptance date:
- 2022-05-11
- DOI:
- EISSN:
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1999-4915
- ISSN:
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1999-4915
- Pmid:
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35632812
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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1260555
- Local pid:
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pubs:1260555
- Deposit date:
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2022-09-26
Terms of use
- Copyright holder:
- Magri et al
- Copyright date:
- 2022
- Rights statement:
- © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
- Licence:
- CC Attribution (CC BY)
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