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RAB11FIP5-deficient mice exhibit cytokine-related transcriptomic signatures

Abstract:

Rab11 recycling endosomes are involved in immunological synaptic functions, but the roles of Rab11 family-interacting protein 5 (Rab11Fip5), one of the Rab11 effectors, in the immune system remain obscure. Our previous study demonstrated that RAB11FIP5 transcripts are significantly elevated in PBMCs from HIV-1-infected individuals, making broadly HIV-1-neutralizing Abs compared with those without broadly neutralizing Abs; however, the role of Rab11FiP5 in immune functions remains unclear. In ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4049/immunohorizons.2000088

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Publisher:
American Association of Immunologists
Journal:
ImmunoHorizons More from this journal
Volume:
4
Issue:
11
Pages:
713-728
Publication date:
2020-11-10
Acceptance date:
2020-10-23
DOI:
EISSN:
2573-7732
ISSN:
2573-7732
Pmid:
33172842
Language:
English
Keywords:
Pubs id:
1145291
Local pid:
pubs:1145291
Deposit date:
2020-11-16

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