- Abstract:
-
B-cell acute lymphoblastic leukemia (B-ALL) is a rare heterogeneous disease characterized by a block in lymphoid differentiation and a rapid clonal expansion of immature, non-functioning B cells. Adult B-ALL patients have a poor prognosis with less than 50% chance of survival after five years and a high relapse rate after allogeneic haematopoietic stem cell transplantation. Novel treatment approaches are required to improve the outcome for patients and the identification of B-ALL specific ant...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.3MB)
-
- Publisher copy:
- 10.18632/oncotarget.23380
-
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- Publisher:
- Impact Journals Publisher's website
- Journal:
- Oncotarget Journal website
- Volume:
- 9
- Issue:
- 3
- Pages:
- 3853-3866
- Publication date:
- 2017-12-17
- Acceptance date:
- 2017-11-26
- DOI:
- ISSN:
-
1949-2553
- Pubs id:
-
pubs:817391
- URN:
-
uri:f64acce5-9b37-4591-997a-d90de23b0967
- UUID:
-
uuid:f64acce5-9b37-4591-997a-d90de23b0967
- Local pid:
- pubs:817391
- Paper number:
- 3
- Copyright holder:
- Boullosa et al.
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 Boullosa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License
3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and
source are credited.
Journal article
Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukaemia
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