Journal article
Identification of survivin as a promising target for the immunotherapy of adult B-cell acute lymphoblastic leukaemia
- Abstract:
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B-cell acute lymphoblastic leukemia (B-ALL) is a rare heterogeneous disease characterized by a block in lymphoid differentiation and a rapid clonal expansion of immature, non-functioning B cells. Adult B-ALL patients have a poor prognosis with less than 50% chance of survival after five years and a high relapse rate after allogeneic haematopoietic stem cell transplantation. Novel treatment approaches are required to improve the outcome for patients and the identification of B-ALL specific ant...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.3MB)
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- Publisher copy:
- 10.18632/oncotarget.23380
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Authors
Funding
Bibliographic Details
- Publisher:
- Impact Journals Publisher's website
- Journal:
- Oncotarget Journal website
- Volume:
- 9
- Issue:
- 3
- Pages:
- 3853-3866
- Publication date:
- 2017-12-17
- Acceptance date:
- 2017-11-26
- DOI:
- ISSN:
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1949-2553
- Source identifiers:
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817391
Item Description
- Keywords:
- Pubs id:
-
pubs:817391
- UUID:
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uuid:f64acce5-9b37-4591-997a-d90de23b0967
- Local pid:
- pubs:817391
- Deposit date:
- 2018-01-10
Terms of use
- Copyright holder:
- Boullosa et al
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 Boullosa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License
3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and
source are credited.
- Licence:
- CC Attribution (CC BY)
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