- Abstract:
-
Diffusion imaging is a promising marker of microstructural damage in neurodegenerative disorders, but interpretation of its relationship with underlying neuropathology can be complex. Here, we examined both volumetric and brain microstructure abnormalities in 13 amnestic patients with mild cognitive impairment (MCI), who progressed to probable Alzheimer's disease (AD) no earlier than 2 years after baseline scanning, in order to focus on early, and hence more sensitive, imaging markers. We com...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1523/jneurosci.4437-12.2013
-
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- Journal:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume:
- 33
- Issue:
- 5
- Pages:
- 2147-2155
- Publication date:
- 2013-01-05
- DOI:
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- URN:
-
uuid:f60cf412-a666-4b54-b6ad-f78a7f8e953c
- Source identifiers:
-
375703
- Local pid:
- pubs:375703
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease.
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