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Variation in human genes encoding adhesion and proinflammatory molecules are associated with severe malaria in the Vietnamese

Abstract:

The genetic basis for susceptibility to malaria has been studied widely in African populations but less is known of the contribution of specific genetic variants in Asian populations. We genotyped 67 single-nucleotide polymorphisms (SNPs) in 1030 severe malaria cases and 2840 controls from Vietnam. After data quality control, genotyping data of 956 cases and 2350 controls were analysed for 65 SNPs (3 gender confirmation, 62 positioned in/near 42 malarial candi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/gene.2012.25

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
Springer Nature
Journal:
Genes and Immunity More from this journal
Volume:
13
Issue:
6
Pages:
503–508
Publication date:
2012-06-07
Acceptance date:
2012-05-02
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Pmid:
22673309
Language:
English
Keywords:
Pubs id:
pubs:334969
UUID:
uuid:f60460f5-0cd1-421c-9f52-ab724217bb9f
Local pid:
pubs:334969
Source identifiers:
334969
Deposit date:
2017-04-26

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