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Journal article

Hypoxia imaging and radiotherapy: bridging the resolution gap

Abstract:

Oxygen distribution is a major determinant of treatment success in radiotherapy, with well-oxygenated tumour regions responding by up to a factor of three relative to anoxic volumes. Conversely, tumour hypoxia is associated with treatment resistance and negative prognosis. Tumour oxygenation is highly heterogeneous and difficult to measure directly. The recent advent of functional hypoxia imaging modalities such as fluorine-18 fluoromisonidazole positron emission tomography have shown promise...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
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Name:
Cancer Research UK
Grant:
C53469/A19834
Publisher:
British Institute of Radiology
Journal:
British Journal of Radiology More from this journal
Volume:
90
Pages:
20160939
Publication date:
2017-05-01
Acceptance date:
2017-04-12
DOI:
EISSN:
1748-880X
ISSN:
0007-1285
Keywords:
Pubs id:
pubs:691224
UUID:
uuid:f5f88962-93be-48f1-86ac-badd01a7f028
Local pid:
pubs:691224
Deposit date:
2017-04-26

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