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Journal article

Comparative effectiveness of improvement in pain and physical function for baricitinib versus adalimumab, tocilizumab, and tofacitinib monotherapies in rheumatoid arthritis patients who are naïve to treatment with biologic or conventional synthetic disease-modifying antirheumatic drugs: A matching-adjusted indirect comparison

Abstract:

Objective:
To compare improvement in pain and physical function for patients treated with baricitinib, adalimumab, tocilizumab and tofacitinib monotherapy from randomised, methotrexate (MTX)-controlled trials in conventional synthetic disease-modifying antirheumatic drugs (csDMARDs)/biologic (bDMARD)-naïve RA patients using matching-adjusted indirect comparisons (MAICs).


Methods:
Data were from Phase III trials on patients receivi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0001-7766-6167
Publisher:
BMJ
Journal:
RMD Open More from this journal
Volume:
6
Issue:
1
Article number:
e001131
Publication date:
2020-05-05
Acceptance date:
2020-03-02
DOI:
EISSN:
2056-5933
ISSN:
2056-5933
Language:
English
Keywords:
Pubs id:
1090964
Local pid:
pubs:1090964
Deposit date:
2020-03-04

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