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Magnetic resonance imaging of brain inflammation using microparticles of iron oxide.

Abstract:

For molecular magnetic resonance imaging (mMRI), microparticles of iron oxide (MPIO) create potent hypointense contrast effects that extend a distance far exceeding their physical size. The potency of the contrast effects derive from their high iron content and are significantly greater than that of ultra-small particles of iron oxide (USPIO), commonly used for MRI. Due to their size and incompressible nature, MPIO are less susceptible to nonspecific vascular egress or uptake by endothelial c...

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Publisher copy:
10.1007/978-1-60761-901-7_7

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Journal:
Methods in molecular biology (Clifton, N.J.)
Volume:
680
Pages:
103-115
Publication date:
2011-01-01
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Source identifiers:
131260
Language:
English
Keywords:
Pubs id:
pubs:131260
UUID:
uuid:f5641c6f-ecd0-456a-922a-84ef34dd1e99
Local pid:
pubs:131260
Deposit date:
2012-12-19

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