Journal article

OTULIN deficiency causes auto-inflammatory syndrome

Abstract:: Ubiquitin chains assembled via the N-terminal methionine (Met1; or linear ubiquitin), conjugated by the linear ubiquitin chain assembly complex (LUBAC), participate in NF- dependent inflammatory signaling and immune responses. A recent report in Cell finds that OTULIN, a deubiquitinase that selectively cleaves Met1-linked ubiquitin chains, is essential for restraining inflammation in vivo.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Gyrd-Hansen, M., & Fiil, B. (2016). OTULIN deficiency causes auto-inflammatory syndrome. Cell Research, 26, 1176–1177.

MLA Style

Gyrd-Hansen, M., and B. Fiil. “OTULIN Deficiency Causes Auto-Inflammatory Syndrome.” Cell Research, vol. 26, Nature Publishing Group, 2016, pp. 1176–77.

Chicago Style

Gyrd-Hansen, M, and B Fiil. 2016. “OTULIN Deficiency Causes Auto-Inflammatory Syndrome.” Cell Research 26: 1176–77.
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Files:: Gyrd-Hansen and Fiil, OTULIN deficiency causes auto-inflammato...

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Publisher copy:: 10.1038/cr.2016.113

Authors

+ Gyrd-Hansen, M More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

+ Fiil, B More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Oxford Ludwig Institute
Role:: Author

Publisher:: Nature Publishing Group
Journal:: Cell Research More from this journal
Volume:: 26
Pages:: 1176-1177
Publication date:: 2016-08-01
Acceptance date:: 2016-08-31
DOI:: 10.1038/cr.2016.113
ISSN:: 1748-7838

Pubs id:: pubs:645751
UUID:: uuid:f4f326df-9948-46b1-901d-f3ef7badf231
Local pid:: pubs:645751
Source identifiers:: 645751
Deposit date:: 2016-09-21

Terms of use

Copyright holder:: IBCB, SIBS, CAS
Copyright date:: 2016
Notes:: © 2016 IBCB, SIBS, CAS All rights reserved

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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