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Journal article

Diagnostic test accuracy of a 2-transcript host RNA signature for discriminating bacterial vs viral infection in febrile children

Abstract:

Importance

Because clinical features do not reliably distinguish bacterial from viral infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infection is missed in others.

Objective

To identify a blood RNA expression signature that distinguishes bacterial from viral infection in febrile children.

Design, Setting, and Participants

Febrile children presenting to participating hospitals in the United Kingdom, Spai...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Files:
Publisher copy:
10.1001/jama.2016.11236

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Publisher:
American Medical Association Publisher's website
Journal:
JAMA Journal website
Volume:
316
Pages:
835-845
Publication date:
2016-08-05
Acceptance date:
2016-07-26
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
Pubs id:
pubs:640586
URN:
uri:f4cedfb6-d71b-45ec-82d7-c0502eaba223
UUID:
uuid:f4cedfb6-d71b-45ec-82d7-c0502eaba223
Local pid:
pubs:640586
Paper number:
8

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