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Analysis of the murine 5-HT receptor gene promoter in vitro and in vivo.

Abstract:

The expression level of the 5-HT(1A) receptor gene (htr1a) in the central nervous system (CNS) is implicated in the aetiology and treatment of anxiety disorders and depression. Previous studies of the murine htr1a have revealed that its proximal promoter is GC rich and TATA-less. Several functional transcription factor binding sites, including MAZ and SP1 recognition sequences, have been identified. To further analyse the promoter of this receptor gene, additional upstream sequence informatio...

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Authors


Ansorge, M More by this author
Tanneberger, C More by this author
Theuring, F More by this author
Kusserow, H More by this author
Journal:
The European journal of neuroscience
Volume:
20
Issue:
2
Pages:
363-374
Publication date:
2004-07-05
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
URN:
uuid:f44a8093-147d-49e4-b73b-925b1e760acf
Source identifiers:
95870
Local pid:
pubs:95870

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