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MRI imaging for sensitive tumour cell-tracking during development of early brain metastasis in a preclinical model

Abstract:

Breast cancer patients frequently develop brain metastases. Conventional treatment is palliative and often involves whole-brain radiotherapy. There is a pressing unmet therapeutic need to treat brainmetastasis at an early stage, when relatively few tumor cells have invaded the brain parenchyma. However, to evaluate the efficacy of new therapeutic treatments, preclinical models of early stage brain metastases and tools to monitor response to treatment are needed. The aim of this study was to d...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1177/0271678X17695991

Authors


Corroyer-Dulmont, A More by this author
Valable, S More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
Subgroup:
CRUK/MRC Ox Inst Radiation Oncology
ORCID:
0000-0003-1211-2766
Bernaudin, M More by this author
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Publisher:
SAGE Publications Publisher's website
Volume:
37
Pages:
323-324
Publication date:
2017-04-01
Acceptance date:
2017-01-13
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
Pubs id:
pubs:720065
URN:
uri:f3af5226-32ba-4100-bc64-67fa43801518
UUID:
uuid:f3af5226-32ba-4100-bc64-67fa43801518
Local pid:
pubs:720065

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