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How Can Genetic Studies Help Us to Understand Links Between Birth Weight and Type 2 Diabetes?

Abstract:

PURPOSE OF REVIEW: In observational epidemiology, both low and high birth weights are associated with later type 2 diabetes. The mechanisms underlying the associations are poorly understood. We review evidence for the roles of genetic and non-genetic factors linking both sides of the birth weight distribution to risk of type 2 diabetes, focusing on contributions made by the most recent genome-wide association studies (GWAS) of birth weight.

RECENT FINDINGS: There are n...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1007/s11892-017-0852-9

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Green Templeton College
Role:
Author
Publisher:
Springer Verlag Publisher's website
Journal:
Current Diabetes Reports
Volume:
17
Issue:
4
Pages:
22
Publication date:
2017-03-14
Acceptance date:
2017-01-01
DOI:
EISSN:
1539-0829
ISSN:
1534-4827
Pubs id:
pubs:686856
URN:
uri:f3948626-ae2c-4acb-b2db-aaf6173bebef
UUID:
uuid:f3948626-ae2c-4acb-b2db-aaf6173bebef
Local pid:
pubs:686856
Paper number:
4

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