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Thesis

Biofluid analysis to differentiate brain disease

Abstract:

It has been demonstrated that by using 1H NMR spectroscopy in combination with multivariate statistical modelling (PLS) it is possible, using urine samples obtained from rats, to distinguish between different types of CNS lesions. Against this background this thesis will explore whether the combination of 1H NMR and PLS modelling on biofluids can be used to identify biomarkers in different neurological diseases and in clinically relevant animal models of neurologic disease. The results in ...

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Oxford college:
New College
Role:
Author
More by this author
Division:
MSD
Department:
Pharmacology
Role:
Author

Contributors

Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:f38ed935-14ad-424e-bbb9-078475dc581a
Deposit date:
2016-11-15

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