- Abstract:
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It has been demonstrated that by using 1H NMR spectroscopy in combination with multivariate statistical modelling (PLS) it is possible, using urine samples obtained from rats, to distinguish between different types of CNS lesions. Against this background this thesis will explore whether the combination of 1H NMR and PLS modelling on biofluids can be used to identify biomarkers in different neurological diseases and in clinically relevant animal models of neurologic disease. The results in ...
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- Role:
- Supervisor
- Role:
- Supervisor
- Institution:
- University of Oxford
- Oxford college:
- New College
- Department:
- Medical Sciences Division - Radiation,Oncology and Biology
- Publication date:
- 2012
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Alex Dickens
- Copyright date:
- 2011
Thesis
Biofluid analysis to differentiate brain disease
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Authors
Contributors
+ Nicola R. Sibson
+ Daniel C. Anthony
+ Alex Mountfort Dickens
Funding
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