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Thesis

Biofluid analysis to differentiate brain disease

Abstract:

It has been demonstrated that by using 1H NMR spectroscopy in combination with multivariate statistical modelling (PLS) it is possible, using urine samples obtained from rats, to distinguish between different types of CNS lesions. Against this background this thesis will explore whether the combination of 1H NMR and PLS modelling on biofluids can be used to identify biomarkers in different neurological diseases and in clinically relevant animal models of neurologic disease. The results in ...

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Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Oxford college:
New College
Department:
Medical Sciences Division - Radiation,Oncology and Biology
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Funding agency for:
Alex Mountfort Dickens
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral

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