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Defective production of and response to IL-2 in acute human falciparum malaria.

Abstract:

Patients with acute Plasmodium falciparum malaria have defective cell-mediated immune responses to malaria-specific Ag (MA). This immunologic defect may partially explain the difficulty with which natural immunity to falciparum malaria develops and may have important implications for the efficacy of potential malaria vaccines in endemic areas. To investigate the basis of this immune defect, we have examined the capacity of PBMC from patients with acute falciparum malaria to produce IL-2 and t...

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Publication status:
Published

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Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
141
Issue:
8
Pages:
2755-2759
Publication date:
1988-10-05
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:f3754a89-0846-46a8-91d4-53d7e911c47f
Source identifiers:
42994
Local pid:
pubs:42994

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