Journal article
Total synthesis of the Schisandraceae nortriterpenoid rubriflordilactone A
- Abstract:
- Full details of the total synthesis of the Schisandraceae nortriterpenoid natural product rubriflordilactone A are reported. Palladium- and cobalt-catalyzed polycyclizations were employed as key strategies to construct the central pentasubstituted arene from bromoendiyne and triyne precursors. This required the independent assembly of two AB ring aldehydes for combination with a common diyne component. A number of model systems were explored to investigate these two methodologies, and also to establish routes for the installation of the challenging benzopyran and butenolide rings.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.7MB, Terms of use)
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- Publisher copy:
- 10.1002/chem.201703229
Authors
+ Agency for Science, Technology and Research (A*STAR), Singapore
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- Grant:
- National Science Scholarship (SSG
+ Engineering and Physical Sciences Research Council
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- Grant:
- additionalfunding(EP/K005391/1
- AdvancedResearchFellowship (EAA)(EP/E055273/1)
+ European Commission
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- Grant:
- Marie Skłodowska-Curie actions for an Individual Fellowship (GC, GA N° 656012
- Publisher:
- Wiley
- Journal:
- Chemistry More from this journal
- Volume:
- 23
- Issue:
- 56
- Pages:
- 14080–14089
- Publication date:
- 2017-09-08
- Acceptance date:
- 2017-08-01
- DOI:
- ISSN:
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1521-3765
- Language:
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English
- Keywords:
- Pubs id:
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pubs:713283
- UUID:
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uuid:f33ab4c4-22b3-4443-9efe-5d038e884be4
- Local pid:
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pubs:713283
- Source identifiers:
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713283
- Deposit date:
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2017-08-11
Terms of use
- Copyright holder:
- Chaubet et al
- Copyright date:
- 2017
- Notes:
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Copyright © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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