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Meta-analysis of epigenome-wide association studies of cognitive abilities

Abstract:

Cognitive functions are important correlates of health outcomes across the life-course. Individual differences in cognitive functions are partly heritable. Epigenetic modifications, such as DNA methylation, are susceptible to both genetic and environmental factors and may provide insights into individual differences in cognitive functions. Epigenome-wide meta-analyses for blood-based DNA methylation levels at ~420,000 CpG sites were performed for seven measures of cognitive functioning using ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0003-4430-4260
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Role:
Author
ORCID:
0000-0001-5286-5485
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Role:
Author
ORCID:
0000-0002-1875-8448
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Role:
Author
ORCID:
0000-0001-6840-072X
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Name:
Chief Scientist Office
Grant:
CZB/4/505
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Name:
Intramural NIH HHS
Grant:
Z01 AG000949-02
Z01 AG000932-01
Z99 AG999999
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Name:
NIAMS NIH HHS
Grant:
R21 AR056405
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Name:
NINDS NIH HHS
Grant:
R01 NS017950
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Name:
NIA NIH HHS
Grant:
R01 AG054076
Publisher:
Nature
Journal:
Molecular Psychiatry More from this journal
Volume:
23
Pages:
2133–2144
Publication date:
2018-01-08
Acceptance date:
2017-10-27
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
Pmid:
29311653
Language:
English
Keywords:
Pubs id:
pubs:953555
UUID:
uuid:f32b6ae3-fb0a-410c-b8ec-6216757a875a
Local pid:
pubs:953555
Source identifiers:
953555
Deposit date:
2019-03-22

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