Journal article icon

Journal article

Controlling compartmentalization by non-membrane-bound organelles

Abstract:

Compartmentalization is a characterizing feature of complexity in cells, used to organize their biochemistry. Membrane-bound organelles are most widely known, but non-membrane-bound liquid organelles also exist. These have recently been shown to form by phase separation of specific types of proteins known as scaffolds. This forms two phases: a condensate that is enriched in scaffold protein separated by a phase boundary from the cytoplasm or nucleoplasm with a low concentration of the scaffol...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1098/rstb.2017.0193

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
ORCID:
0000-0002-4270-8360
More by this author
ORCID:
0000-0003-3664-154X
More from this funder
Funding agency for:
Wheeler, RJ
Publisher:
Royal Society Publisher's website
Journal:
Philosophical Transactions of the Royal Society B: Biological Sciences Journal website
Volume:
373
Issue:
1747
Pages:
Article: 20170193
Publication date:
2018-04-09
Acceptance date:
2017-12-30
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
Pubs id:
pubs:844061
URN:
uri:f31699e2-e212-4978-88c4-ba47da3f1e28
UUID:
uuid:f31699e2-e212-4978-88c4-ba47da3f1e28
Local pid:
pubs:844061

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP