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Journal article

Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene-environment interaction effects on adult blood pressure and hypertension status in adulthood

Abstract:

Background

Genetic variants may modify the associations of adiposity measures with blood pressure (BP) and hypertension. The insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene is an attractive candidate.

Aims

To examine interaction effects between I/D polymorphism and adiposity measures (BMI, waist circumference, waist-to-hip ratio, and skinfold thickness) during childhood and adulthood in relation to adult BP and hypertension.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
Journal of Hypertension Journal website
Volume:
36
Issue:
11
Pages:
2168-2176
Publication date:
2018-11-01
Acceptance date:
2018-05-08
DOI:
EISSN:
1473-5598
ISSN:
0263-6352
Pubs id:
pubs:865319
URN:
uri:f30b07e9-1ef3-4d15-be5d-6586e63ba924
UUID:
uuid:f30b07e9-1ef3-4d15-be5d-6586e63ba924
Local pid:
pubs:865319

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