Case-control vaccine effectiveness studies: Preparation, design, and enrollment of cases and controls.
Case-control studies are commonly used to evaluate effectiveness of licensed vaccines after deployment in public health programs. Such studies can provide policy-relevant data on vaccine performance under 'real world' conditions, contributing to the evidence base to support and sustain introduction of new vaccines. However, case-control studies do not measure the impact of vaccine introduction on disease at a population level, and are subject to bias and confounding, which may lead to inaccur...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Version of record, pdf, 369.1KB)
- Publisher copy:
- Copyright holder:
- Verani et al
- Copyright date:
- © the Author(s) 2017. Published by Elsevier Ltd., available under a Creative Commons license.
If you are the owner of this record, you can report an update to it here: Report update to this record