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Health-related quality of life impact of minor and major bleeding events during dual antiplatelet therapy: a systematic literature review and patient preference elicitation study

Abstract:

Background

Dual antiplatelet therapy (DAPT) is the recommended preventative treatment for secondary ischaemic events, but increases the risk of bleeding, potentially affecting patients’ health-related quality-of-life (HRQoL). Varied utility decrements have been used in cost-effectiveness models assessing alternative DAPT regimens, but it is unclear which of these decrements are most appropriate. Therefore, we reviewed existing sources of utility decrements for bleeds in patients ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12955-018-1019-3

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Dept of Population Health
Role:
Author
ORCID:
0000-0002-4948-8831
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Strategic
Role:
Author
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Publisher:
BioMed Central Publisher's website
Journal:
Health and Quality of Life Outcomes Journal website
Volume:
16
Issue:
1
Pages:
191
Publication date:
2018-09-20
Acceptance date:
2018-09-11
DOI:
EISSN:
1477-7525
ISSN:
1477-7525
Pubs id:
pubs:922108
URN:
uri:f2bfd391-f5a0-4e45-914e-677093aec9f3
UUID:
uuid:f2bfd391-f5a0-4e45-914e-677093aec9f3
Local pid:
pubs:922108

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