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Automated solid-phase extraction method for the determination of piperaquine in whole blood by rapid liquid chromatography.

Abstract:

A bioanalytic method for the determination of piperaquine in whole blood by solid-phase extraction and rapid liquid chromatography has been developed and validated. Whole blood was hemolyzed with deionized water, and an internal standard was added to the samples before they were loaded onto a PRS cation-exchange solid-phase extraction column. Piperaquine and internal standard were analyzed by liquid chromatography on a Chromolith Performance (100 x 4.6 mm) column with mobile phase acetonitril...

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Publisher copy:
10.1097/00007691-200310000-00002
Journal:
Therapeutic drug monitoring More from this journal
Volume:
25
Issue:
5
Pages:
544-551
Publication date:
2003-10-01
DOI:
EISSN:
1536-3694
ISSN:
0163-4356
Language:
English
Keywords:
Pubs id:
pubs:5573
UUID:
uuid:f2bc86cf-3b74-4429-bc7e-6b890d17f086
Local pid:
pubs:5573
Source identifiers:
5573
Deposit date:
2013-02-20

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