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Journal article

Between-trial heterogeneity in ARDS research

Abstract:

Purpose Most randomized controlled trials (RCTs) in patients with acute respiratory distress syndrome (ARDS) revealed indeterminate or conflicting study results. We aimed to systematically evaluate between-trial heterogeneity in reporting standards and trial outcome. Methods A systematic review of RCTs published between 2000 and 2019 was performed including adult ARDS patients receiving lung-protective ventilation. A random-effects meta-regression model was applied to quantify heterogeneity ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0003-2176-5072
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Publisher:
Springer
Journal:
Intensive Care Medicine More from this journal
Volume:
47
Issue:
4
Pages:
422-434
Publication date:
2021-03-13
Acceptance date:
2021-02-15
DOI:
EISSN:
1432-1238
ISSN:
0342-4642
Pmid:
33713156
Language:
English
Keywords:
Pubs id:
1181091
Local pid:
pubs:1181091
Deposit date:
2022-01-11

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