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Single-cell multi-omics characterise discrete human tendon cells populations that persist in vitro and on fibrous scaffolds

Abstract:

Chronic tendinopathy represents a growing healthcare burden in the ageing global population. Curative therapies remain elusive as the mechanisms that underlie chronic inflammation in tendon disease remain unclear. Identifying and isolating key pathogenic and reparative cells is essential in developing precision therapies and implantable materials for improved tendon healing. Multiple discrete human tendon cell populations have been previously described ex vivo. To determine if these populatio...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.22203/eCM.v044a01

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
More by this author
Institution:
Oxford University Hospitals
Research group:
Nuffield Orthopaedic Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0003-2470-1031
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
Publisher:
AO Research Institute Davos
Journal:
European Cells & Materials More from this journal
Volume:
44
Pages:
1-20
Place of publication:
Switzerland
Publication date:
2022-08-02
Acceptance date:
2022-05-17
DOI:
EISSN:
1473-2262
Pmid:
35916474

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