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The gut-microbiome as a target for the treatment of schizophrenia: A systematic review and meta-analysis of randomised controlled trials of add-on strategies

Abstract:

The gut-microbiome has been hypothesised as a novel potential target for intervention for schizophrenia.

We tested this hypothesis with a systematic review and meta-analysis of studies investigating the efficacy and acceptability of add-on strategies known to affect the gut-microbiome for the treatment of schizophrenia.

Following PRISMA guidelines, we searched from inception to August 2019 all the randomised double-blind controlled trials of add-on antibiotics, antimicrobia...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
Elsevier
Journal:
Schizophrenia Research More from this journal
Volume:
234
Pages:
58-70
Publication date:
2020-04-12
Acceptance date:
2020-02-28
DOI:
EISSN:
1573-2509
ISSN:
0920-9964
Language:
English
Keywords:
Pubs id:
1095456
Local pid:
pubs:1095456
Deposit date:
2020-03-20

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